Turner 1999 Internal Loop Example 3

example structure

∆G°₃₇ = ∆G°₃₇(Watson-Crick Pairs) + ∆G°_{37 intermolecular initiation} + ∆G°₃₇(Internal Loop)

∆G°₃₇ = ∆G°₃₇(CG followed by AU) + ∆G°₃₇(CG followed by GC) + ∆G°_{37 intermolecular initiation}+ ∆G°_{37 initiation}(5) + ΔG°_{37 asymmetry}×| n₁ - n₂| + ΔG°_{37 mismatch}(mismatch 1) + ΔG°_{37 mismatch}(mismatch 2) + ΔG°_{37 AU/GU closure}

∆G°₃₇ = –2.11 kcal/mol – 2.36 kcal/mol + 4.09 kcal/mol + 1.8 kcal/mol + 0.48×|2 - 3| kcal/mol – 0.0 kcal/mol – 1.1 kcal/mol + 0.65 kcal/mol

∆G°₃₇ = +1.5 kcal/mol

Turner 1999
Internal Loop Example 3

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