Navigator:

Homepage

Turner 1999

Internal Loops

Example 3

 

 

example structure        

∆G°37 = ∆G°37(Watson-Crick Pairs) + ∆G°37 intermolecular initiation + ∆G°37(Internal Loop)

 

∆G°37 = ∆G°37(CG followed by AU) + ∆G°37(CG followed by GC) + ∆G°37 intermolecular initiation+ ∆G°37 initiation(5) + ΔG°37 asymmetry×| n1 - n2| + ΔG°37 mismatch(mismatch 1) + ΔG°37 mismatch(mismatch 2) + ΔG°37 AU/GU closure

 

∆G°37 = –2.11 kcal/mol 2.36 kcal/mol + 4.09 kcal/mol + 1.8 kcal/mol + 0.48×|2 - 3| kcal/mol – 0.0 kcal/mol – 1.1 kcal/mol + 0.65 kcal/mol

 

∆G°37 = +1.5 kcal/mol