Turner 1999 Hairpin Example 5

example structure

∆G°₃₇ = ∆G°₃₇(Watson-Crick Pairs) + ∆G°₃₇(Hairpin Loop)

∆G°₃₇ = ∆G°₃₇(Watson-Crick Pairs) + ∆G°₃₇(terminal mismatch) + ∆G°_{37 Hairpin initiation}(5) + ΔG°₃₇(special GU closure)

∆G°₃₇ = ∆G°₃₇(CG followed by GC) + ∆G°₃₇(GC followed by GC) + ∆G°₃₇(GC followed by GU) + ∆G°_{37 GU end penalty}+ ∆G°₃₇(GU followed by GG) + ∆G°_{37 Hairpin initiation}(5) + ΔG°₃₇(special GU closure)

∆G°₃₇ = –2.36 kcal/mol – 3.26 kcal/mol – 1.53 kcal/mol + 0.45 kcal/mol – 0.8 kcal/mol + 5.6 kcal/mol – 2.2 kcal/mol

∆G°₃₇ = –4.1 kcal/mol

Turner 1999
Hairpin Example 5

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