Turner 1999

Coaxial Stacking




The coaxial stacking nearest neighbor parameters for free energy change were reported in:

Mathews, D.H., Sabina, J., Zuker, M. and Turner, D.H. (1999) Expanded sequence dependence of thermodynamic parameters provides improved prediction of RNA secondary structure. J. Mol. Biol., 288, 911-940.


The experimental data for the fit of the parameters were taken from:

1.       Walter, A.E., Turner, D.H., Kim, J., Lyttle, M.H., Müller, P., Mathews, D.H. and Zuker, M. (1994) Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding. Proc. Natl. Acad. Sci. USA., 91, 9218-9222.

2.       Kim, J., Walter, A.E. and Turner, D.H. (1996) Thermodynamics of coaxially stacked helices with GA and CC mismatches. Biochemistry, 35, 13753-13761.