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Turner 1999

Bulge Loops

Example 2

 

 

example structure        

∆G°37 = ∆G°37(Watson-Crick Pairs) + ∆G°37 intermolecular initiation + ∆G°37 AU end penalty + ∆G°37(Bulge Loop)


∆G
°37 = ∆G°37(GC followed by AU) +∆G°37 intermolecular initiation + ∆G°37 AU end penalty + ∆G°37 bulge initiation(3)

 

∆G°37 = –2.35 kcal/mol + 4.09 kcal/mol + 0.45 kcal/mol + 3.2 kcal/mol

 

∆G°37 = +5.4 kcal/mol