Data table for symetric interior loops of size 2

Free energies at 37 degrees for RNA

Data Arrangement:

Y

------------------

(X) A C G U

------------------

5' --> 3'

X

A A

U U

Y

3' <-- 5'

(A) . . . .

(C) . . . .

(G) . . . .

(U) . . . .

Y Y Y Y Y Y

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

A C G U A C G U A C G U A C G U A C G U A C G U

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'

X X X X X X

A A A C A G A U A G A U

U U U G U C U A U U U G

Y Y Y Y Y Y

3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'

1.9 1.9 1.9 1.9 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 1.9 1.9 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 -0.7 1.9 1.2 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9

1.9 1.9 1.9 1.5 1.2 1.2 1.2 0.8 1.2 1.2 1.2 0.8 1.9 1.9 1.9 1.2 1.9 1.9 1.9 1.6 1.9 1.9 1.9 1.2

Y Y Y Y Y Y

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

A C G U A C G U A C G U A C G U A C G U A C G U

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'

X X X X X X

C A C C C G C U C G C U

G U G G G C G A G U G G

Y Y Y Y Y Y

3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'

1.2 1.2 1.2 1.2 0.9 -0.4 0.5 0.5 0.9 0.5 0.5 0.5 1.2 1.2 1.2 1.2 2.2 1.3 1.2 1.2 0.6 0.5 1.2 1.2

1.2 1.2 1.2 1.2 0.3 0.5 0.5 0.6 0.5 0.5 0.5 0.5 1.2 1.2 1.2 1.2 1.2 1.7 1.2 1.2 1.2 1.2 1.2 1.2

1.2 1.2 -1.4 1.2 -0.1 0.5 -2.2 0.5 0.5 0.5 -1.4 0.5 1.2 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2 -0.2 1.2 -1.4 1.2

1.2 1.2 1.2 1.2 0.5 0.0 0.5 -0.1 0.5 0.5 0.5 0.4 1.2 1.2 1.2 0.8 1.2 1.2 1.2 1.1 1.2 1.0 1.2 1.1

Y Y Y Y Y Y

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

A C G U A C G U A C G U A C G U A C G U A C G U

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'

X X X X X X

G A G C G G G U G G G U

C U C G C C C A C U C G

Y Y Y Y Y Y

3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'

1.2 1.2 1.2 1.2 0.8 0.5 0.5 0.5 0.9 0.3 -0.1 0.5 1.2 1.2 1.2 1.2 1.6 1.2 1.0 1.2 1.9 1.2 1.5 1.2

1.2 1.2 1.2 1.2 0.5 0.5 0.5 0.5 -0.4 0.5 0.5 0.0 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2

1.2 1.2 -1.4 1.2 0.5 0.5 -2.3 0.5 0.5 0.5 -2.2 0.5 1.2 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2

1.2 1.2 1.2 1.2 0.5 0.5 0.5 -0.6 0.5 0.6 0.5 -0.1 1.2 1.2 1.2 0.8 1.2 1.2 1.2 0.7 1.2 1.2 1.2 1.5

Y Y Y Y Y Y

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

A C G U A C G U A C G U A C G U A C G U A C G U

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'

X X X X X X

U A U C U G U U U G U U

A U A G A C A A A U A G

Y Y Y Y Y Y

3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'

1.9 1.9 1.9 1.9 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 1.9 1.9 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 -0.7 1.9 1.2 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9

1.9 1.9 1.9 1.7 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.9 1.9 1.9 1.5 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.6

Y Y Y Y Y Y

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

A C G U A C G U A C G U A C G U A C G U A C G U

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'

X X X X X X

G A G C G G G U G G G U

U U U G U C U A U U U G

Y Y Y Y Y Y

3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'

1.9 1.9 1.9 1.9 1.9 1.2 1.2 1.2 0.6 1.2 -0.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 1.9 1.9 1.2 1.2 1.2 1.2 0.5 1.2 1.2 1.0 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 -0.7 1.9 1.5 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9

1.9 1.9 1.9 1.6 1.2 1.2 1.2 1.5 1.2 1.2 1.2 1.1 1.9 1.9 1.9 1.2 1.9 1.9 1.9 1.6 1.9 1.9 1.9 1.2

Y Y Y Y Y Y

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

A C G U A C G U A C G U A C G U A C G U A C G U

------------------ ------------------ ------------------ ------------------ ------------------ ------------------

5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'

X X X X X X

U A U C U G U U U G U U

G U G G G C G A G U G G

Y Y Y Y Y Y

3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'

1.9 1.9 1.9 1.9 1.6 1.2 1.2 1.2 2.2 1.2 1.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 1.9 1.9 1.2 1.2 1.2 1.2 1.3 1.7 1.2 1.2 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9

1.9 1.9 -0.7 1.9 1.0 1.2 -1.4 1.2 1.2 1.2 -1.4 1.2 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9 1.9 1.9 -0.7 1.9

1.9 1.9 1.9 1.9 1.2 1.2 1.2 0.7 1.2 1.2 1.2 1.1 1.9 1.9 1.9 1.6 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.6