Parameter

ΔG°37
(kcal/mol)

ΔH°
(kcal/mol)

Symmetrically Equivalent Parameter

5'AA3'
5'UU3'

–0.93 ± 0.03

–6.82 ± 0.79

5'UU3'
3'AA5'

5'AU3'
3'UA5'

–1.10 ± 0.08

–9.38 ± 1.68

 

5'UA3'
3'AU5'

–1.33 ± 0.09

–7.69 ± 2.02

 

5'CU3'
3'GA5'

–2.08 ± 0.06

–10.48 ± 1.24

5'AG3'
3'UC5'

5'CA3'
3'GU5'

–2.11 ± 0.07

–10.44 ± 1.28

5'UG3'
3'AC5'

5'GU3'
3'CA5'

–2.24 ± 0.06

–11.40 ± 1.23

5'AC3'
3'UG5'

5'GA3'
3'CU5'

–2.35 ± 0.06

–12.44 ± 1.20

5'UC3'
3'AG5'

5'CG3'
3'GC5'

–2.36 ± 0.09

–10.64 ± 1.65

 

5'GG3'
3'CC5'

–3.26 ± 0.07

–13.39 ± 1.24

5'CC3'
3'GG5'

5'GC3'
3'CG5'

–3.42 ± 0.08

–14.88 ± 1.58

 

Intermolecular Initiation

+4.09 ± 0.22

+3.61 ± 4.12

 

Per AU end

+0.45 ± 0.04

+3.72 ± 0.83

 

Symmetry correction

+0.43

0.0