Data tables for asymmetric interior loops of size 3
Free energies at 37 degrees for RNA
Data arrangement:
Y
------------------
(X) A C G U
------------------
5' --> 3'
X
A A
U U
YA
3' <-- 5'
(A) . . . .
(C) . . . .
(G) . . . .
(U) . . . .
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
A A A C A G A U A G A U
U U U G U C U A U U U G
YA YA YA YA YA YA
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.9 3.7 3.1 5.5 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5
3.8 3.7 5.5 3.7 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7
3.2 5.5 2.3 5.5 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
A A A C A G A U A G A U
U U U G U C U A U U U G
YC YC YC YC YC YC
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.6 3.2 3.1 5.5 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5
3.7 4.0 5.5 3.7 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.7 5.5 2.8 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
A A A C A G A U A G A U
U U U G U C U A U U U G
YG YG YG YG YG YG
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
2.5 2.1 1.9 5.5 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
2.3 5.5 3.7 5.5 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
A A A C A G A U A G A U
U U U G U C U A U U U G
YU YU YU YU YU YU
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
4.0 3.4 5.5 3.7 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.2 5.5 2.7 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
C A C C C G C U C G C U
G U G G G C G A G U G G
YA YA YA YA YA YA
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.2 3.0 2.4 4.8 2.3 2.2 1.1 4.0 2.4 2.2 1.6 4.0 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8
3.1 3.0 4.8 3.0 2.3 2.2 4.0 2.2 2.3 2.2 4.0 2.2 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0
2.5 4.8 1.6 4.8 1.7 4.0 0.8 4.0 1.7 4.0 0.8 4.0 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
C A C C C G C U C G C U
G U G G G C G A G U G G
YC YC YC YC YC YC
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
2.9 2.5 2.4 4.8 2.1 1.7 1.6 4.0 2.1 1.7 1.6 4.0 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8
3.0 3.3 4.8 3.0 2.2 2.5 4.0 2.2 2.2 2.5 4.0 2.2 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
4.8 3.0 4.8 2.1 4.0 2.2 4.0 1.5 4.0 2.2 4.0 1.3 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
C A C C C G C U C G C U
G U G G G C G A G U G G
YG YG YG YG YG YG
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
1.8 1.4 1.2 4.8 0.8 0.6 0.4 4.0 1.0 0.6 0.4 4.0 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
1.6 4.8 3.0 4.8 0.8 4.0 2.2 4.0 0.8 4.0 2.2 4.0 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
C A C C C G C U C G C U
G U G G G C G A G U G G
YU YU YU YU YU YU
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
3.3 2.7 4.8 3.0 2.5 1.9 4.0 2.2 2.5 1.9 4.0 2.2 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
4.8 2.5 4.8 2.0 4.0 1.7 4.0 1.2 4.0 1.7 4.0 1.2 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
C U C G C C C A C U C G
YA YA YA YA YA YA
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.2 3.0 2.4 4.8 2.4 2.2 1.6 4.0 2.5 2.2 2.1 4.0 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8
3.1 3.0 4.8 3.0 2.3 2.2 4.0 2.2 2.3 2.2 4.0 2.2 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0
2.5 4.8 1.6 4.8 1.7 4.0 0.8 4.0 1.7 4.0 0.8 4.0 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
C U C G C C C A C U C G
YC YC YC YC YC YC
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
2.9 2.5 2.4 4.8 2.1 1.7 1.6 4.0 2.1 1.7 1.6 4.0 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8
3.0 3.3 4.8 3.0 2.2 2.5 4.0 2.2 2.2 2.5 4.0 2.2 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
4.8 3.0 4.8 2.1 4.0 2.2 4.0 1.3 4.0 2.2 4.0 1.2 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
C U C G C C C A C U C G
YG YG YG YG YG YG
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
1.8 1.4 1.2 4.8 1.0 0.6 0.4 4.0 1.2 0.6 0.4 4.0 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
1.6 4.8 3.0 4.8 0.8 4.0 2.2 4.0 0.8 4.0 2.2 4.0 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
C U C G C C C A C U C G
YU YU YU YU YU YU
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
3.3 2.7 4.8 3.0 2.5 1.9 4.0 2.2 2.5 1.9 4.0 2.2 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0
4.8 4.8 4.8 4.8 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8
4.8 2.5 4.8 2.0 4.0 1.7 4.0 1.2 4.0 1.7 4.0 1.2 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
A U A G A C A A A U A G
YA YA YA YA YA YA
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.9 3.7 3.1 5.5 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5
3.8 3.7 5.5 3.7 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7
3.2 5.5 2.3 5.5 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
A U A G A C A A A U A G
YC YC YC YC YC YC
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.6 3.2 3.1 5.5 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5
3.7 4.0 5.5 3.7 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.7 5.5 2.8 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
A U A G A C A A A U A G
YG YG YG YG YG YG
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
2.5 2.1 1.9 5.5 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
2.3 5.5 3.7 5.5 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
A U A G A C A A A U A G
YU YU YU YU YU YU
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
4.0 3.4 5.5 3.7 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.2 5.5 2.7 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
U U U G U C U A U U U G
YA YA YA YA YA YA
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.9 3.7 3.1 5.5 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5
3.8 3.7 5.5 3.7 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7
3.2 5.5 2.3 5.5 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
U U U G U C U A U U U G
YC YC YC YC YC YC
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.6 3.2 3.1 5.5 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5
3.7 4.0 5.5 3.7 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.7 5.5 2.8 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
U U U G U C U A U U U G
YG YG YG YG YG YG
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
2.5 2.1 1.9 5.5 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
2.3 5.5 3.7 5.5 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
G A G C G G G U G G G U
U U U G U C U A U U U G
YU YU YU YU YU YU
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
4.0 3.4 5.5 3.7 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.2 5.5 2.7 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
G U G G G C G A G U G G
YA YA YA YA YA YA
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.9 3.7 3.1 5.5 3.2 3.0 2.4 4.8 3.2 3.0 2.4 4.8 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5 3.9 3.7 3.1 5.5
3.8 3.7 5.5 3.7 3.1 3.0 4.8 3.0 3.1 3.0 4.8 3.0 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7 3.8 3.7 5.5 3.7
3.2 5.5 2.3 5.5 2.5 4.8 1.6 4.8 2.5 4.8 1.6 4.8 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5 3.2 5.5 2.3 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
G U G G G C G A G U G G
YC YC YC YC YC YC
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
3.6 3.2 3.1 5.5 2.9 2.5 2.4 4.8 2.9 2.5 2.4 4.8 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5 3.6 3.2 3.1 5.5
3.7 4.0 5.5 3.7 3.0 3.3 4.8 3.0 3.0 3.3 4.8 3.0 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7 3.7 4.0 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.7 5.5 2.8 4.8 3.0 4.8 2.1 4.8 3.0 4.8 2.1 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8 5.5 3.7 5.5 2.8
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
G U G G G C G A G U G G
YG YG YG YG YG YG
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
2.5 2.1 1.9 5.5 1.8 1.4 1.2 4.8 1.8 1.4 1.2 4.8 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5 2.5 2.1 1.9 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
2.3 5.5 3.7 5.5 1.6 4.8 3.0 4.8 1.6 4.8 3.0 4.8 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5 2.3 5.5 3.7 5.5
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
Y Y Y Y Y Y
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
A C G U A C G U A C G U A C G U A C G U A C G U
------------------ ------------------ ------------------ ------------------ ------------------ ------------------
5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3' 5' --> 3'
X X X X X X
U A U C U G U U U G U U
G U G G G C G A G U G G
YU YU YU YU YU YU
3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5' 3' <-- 5'
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
4.0 3.4 5.5 3.7 3.3 2.7 4.8 3.0 3.3 2.7 4.8 3.0 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7 4.0 3.4 5.5 3.7
5.5 5.5 5.5 5.5 4.8 4.8 4.8 4.8 4.8 4.8 4.8 4.8 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5
5.5 3.2 5.5 2.7 4.8 2.5 4.8 2.0 4.8 2.5 4.8 2.0 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7 5.5 3.2 5.5 2.7