# 5' --> 3' X A A U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A A U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A A U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A A U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A A U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X A M U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A M U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A M U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A M U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A M U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X A C U G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A C U G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A C U G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A C U G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A C U G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X A G U C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A G U C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A G U C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A G U C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X A G U C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X A U U A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X A U U M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X A U U M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X A G U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A G U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A G U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A G U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A G U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X A U U G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A U U G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A U U G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A U U G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X A U U G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X M A U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M A U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M A U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M A U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M A U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X M M U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M M U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M M U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M M U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M M U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X M C U G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M C U G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M C U G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M C U G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M C U G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X M G U C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M G U C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M G U C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M G U C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X M G U C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X M U U A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X M U U M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X M U U M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 3.7 3.7 A 3.7 3.7 3.7 3.7 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X M G U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M G U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M G U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M G U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M G U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X M U U G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M U U G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M U U G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M U U G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X M U U G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X C A G U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C A G U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C A G U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C A G U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C A G U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X C M G U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C M G U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C M G U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C M G U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C M G U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X C C G G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.3 1.1 2.3 A 2.5 2.5 2.3 1.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.7 1.7 2.3 0.8 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C C G G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.3 1.1 2.3 A 2.5 2.5 2.3 1.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.7 1.7 2.3 0.8 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C C G G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 1.7 1.1 2.3 A 2.3 2.3 1.7 1.1 2.3 C 2.3 2.3 2.5 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 2.3 2.3 2.2 2.3 1.5 # 5' --> 3' X C C G G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 0.8 0.8 1.1 1.1 1.1 A 0.8 0.8 1.1 1.1 1.1 C 2.3 2.3 2.3 2.3 2.3 G 1.2 1.2 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C C G G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 1.1 2.3 A 2.3 2.3 2.3 1.1 2.3 C 2.5 2.5 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 1.5 1.5 1.7 1.5 1.4 # 5' --> 3' X C G G C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 1.1 2.3 A 2.3 2.3 2.3 1.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C G G C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 1.1 2.3 A 2.3 2.3 2.3 1.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C G G C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 1.1 2.3 A 2.3 2.3 2.3 1.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C G G C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.1 1.1 1.1 1.1 1.1 A 1.1 1.1 1.1 1.1 1.1 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X C G G C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 1.1 2.3 A 2.3 2.3 2.3 1.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 1.5 1.5 1.5 1.5 1.5 # 5' --> 3' X C U G A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X C U G M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X C U G M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X C G G U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C G G U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C G G U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C G G U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.4 1.4 1.4 1.4 1.4 A 1.4 1.4 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C G G U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X C U G G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C U G G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C U G G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C U G G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.4 1.4 1.4 1.4 1.4 A 1.4 1.4 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X C U G G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X G A C U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G A C U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G A C U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G A C U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G A C U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X G M C U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G M C U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G M C U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G M C U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G M C U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X G C C G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 2.3 2.3 A 2.3 2.3 2.3 2.3 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G C C G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 2.3 2.3 A 2.3 2.3 2.3 2.3 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 0.9 2.3 1.1 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G C C G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 2.3 2.3 A 2.3 2.3 2.3 2.3 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G C C G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.1 1.1 1.1 1.1 1.1 A 1.1 1.1 1.1 1.1 1.1 C 2.3 2.3 2.3 2.3 2.3 G 1.1 2.7 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G C C G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 2.3 2.3 A 2.3 2.3 2.3 2.3 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 1.5 1.5 1.5 1.5 1.5 # 5' --> 3' X G G C C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.3 2.1 2.3 A 2.5 2.5 2.3 2.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G G C C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.3 2.1 2.3 A 2.5 2.5 2.3 2.1 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G G C C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 2.3 2.3 A 2.3 2.3 2.3 2.3 2.3 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G G C C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.2 1.2 1.1 1.1 1.1 A 1.2 1.2 1.1 1.1 1.1 C 2.3 2.3 2.3 2.3 2.3 G 1.1 1.1 1.1 1.1 1.1 U 2.3 2.3 2.3 2.3 1.5 # 5' --> 3' X G G C C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.3 2.3 2.3 2.3 2.3 A 2.3 2.3 2.3 2.3 2.3 C 2.3 2.3 1.9 2.3 2.3 G 1.1 1.1 2.3 1.1 2.3 U 1.5 1.5 1.5 1.5 1.5 # 5' --> 3' X G U C A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X G U C M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X G U C M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 3.0 3.0 A 3.0 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X G G C U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.0 2.0 2.5 1.6 2.5 A 2.0 2.0 2.5 1.6 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G C U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.0 2.0 2.5 1.6 2.5 A 2.0 2.0 2.5 1.6 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G C U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G C U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 0.7 0.7 1.4 1.4 1.4 A 0.7 0.7 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G C U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 1.4 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X G U C G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G U C G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G U C G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G U C G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.4 1.4 1.4 1.4 1.4 A 1.4 1.4 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G U C G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X U A A U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A A U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A A U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A A U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A A U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U M A U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M A U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M A U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M A U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M A U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U C A G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C A G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C A G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C A G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C A G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X U G A C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G A C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G A C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G A C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G A C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X U U A A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U U A M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U A M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U G A U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G A U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G A U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G A U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G A U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U U A G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U A G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U A G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U A G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U A G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U A M U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A M U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A M U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A M U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U A M U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U M M U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M M U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M M U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M M U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U M M U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U C M G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C M G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 0.8 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C M G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C M G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 0.6 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U C M G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X U G M C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G M C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G M C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G M C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.9 1.9 1.9 1.9 1.9 A 1.9 1.9 1.9 1.9 1.9 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 1.9 1.9 1.9 U 3.0 3.0 3.0 3.0 2.2 # 5' --> 3' X U G M C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.0 3.0 3.0 1.9 3.0 A 3.0 3.0 3.0 1.9 3.0 C 3.0 3.0 3.0 3.0 3.0 G 1.9 1.9 3.0 1.9 3.0 U 2.2 2.2 2.2 2.2 2.2 # 5' --> 3' X U U M A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U U M M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.6 2.6 2.6 2.6 2.6 A 2.6 2.6 2.6 2.6 2.6 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 2.6 2.6 2.6 U 3.7 3.7 3.7 3.7 3.0 # 5' --> 3' X U U M M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.7 3.7 3.7 2.6 3.7 A 3.7 3.7 3.7 2.6 3.7 C 3.7 3.7 3.7 3.7 3.7 G 2.6 2.6 3.7 2.6 3.7 U 3.0 3.0 3.0 3.0 3.0 # 5' --> 3' X U G M U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G M U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G M U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G M U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U G M U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U U M G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U M G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U M G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U M G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U M G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X G A U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G A U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G A U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G A U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G A U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X G M U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G M U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G M U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G M U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G M U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X G C U G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G C U G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G C U G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G C U G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.4 1.4 1.4 1.4 1.4 A 1.4 1.4 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G C U G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X G G U C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.0 2.0 2.5 1.6 2.5 A 2.0 2.0 2.5 1.6 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G U C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.0 2.0 2.5 1.6 2.5 A 2.0 2.0 2.5 1.6 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G U C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G U C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 0.7 0.7 1.4 1.4 1.4 A 0.7 0.7 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X G G U C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 2.5 2.5 A 2.5 2.5 2.5 2.5 2.5 C 2.5 2.5 1.4 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X G U U A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X G U U M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X G U U M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 3.2 3.2 A 3.2 3.2 3.2 3.2 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X G G U U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.5 1.5 2.7 1.1 2.7 A 1.5 1.5 2.7 1.1 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G G U U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.5 1.5 2.7 1.1 2.7 A 1.5 1.5 2.7 1.1 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G G U U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 2.7 2.7 A 2.7 2.7 2.7 2.7 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G G U U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 0.2 0.2 1.6 1.6 1.6 A 0.2 0.2 1.6 1.6 1.6 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G G U U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 2.7 2.7 A 2.7 2.7 2.7 2.7 2.7 C 2.7 2.7 0.9 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.0 2.0 2.0 2.0 2.0 # 5' --> 3' X G U U G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 2.7 2.7 A 2.7 2.7 2.7 2.7 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G U U G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 2.7 2.7 A 2.7 2.7 2.7 2.7 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G U U G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 2.7 2.7 A 2.7 2.7 2.7 2.7 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G U U G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.6 1.6 1.6 1.6 1.6 A 1.6 1.6 1.6 1.6 1.6 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X G U U G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 2.7 2.7 A 2.7 2.7 2.7 2.7 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.0 2.0 2.0 2.0 2.0 # 5' --> 3' X U A G U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U A G U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U A G U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U A G U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U A G U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U M G U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U M G U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U M G U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U M G U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U M G U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U C G G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U C G G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U C G G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U C G G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.4 1.4 1.4 1.4 1.4 A 1.4 1.4 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U C G G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X U G G C YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U G G C YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U G G C YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U G G C YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.4 1.4 1.4 1.4 1.4 A 1.4 1.4 1.4 1.4 1.4 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 1.4 1.4 1.4 U 2.5 2.5 2.5 2.5 1.7 # 5' --> 3' X U G G C YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.5 2.5 2.5 1.4 2.5 A 2.5 2.5 2.5 1.4 2.5 C 2.5 2.5 2.5 2.5 2.5 G 1.4 1.4 2.5 1.4 2.5 U 1.7 1.7 1.7 1.7 1.7 # 5' --> 3' X U U G A YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G A YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G A YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G A YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G A YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U U G M YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G M YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G M YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G M YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.1 2.1 2.1 2.1 2.1 A 2.1 2.1 2.1 2.1 2.1 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 2.1 2.1 2.1 U 3.2 3.2 3.2 3.2 2.5 # 5' --> 3' X U U G M YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 3.2 3.2 3.2 2.1 3.2 A 3.2 3.2 3.2 2.1 3.2 C 3.2 3.2 3.2 3.2 3.2 G 2.1 2.1 3.2 2.1 3.2 U 2.5 2.5 2.5 2.5 2.5 # 5' --> 3' X U G G U YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U G G U YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U G G U YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U G G U YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.6 1.6 1.6 1.6 1.6 A 1.6 1.6 1.6 1.6 1.6 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U G G U YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.0 2.0 2.0 2.0 2.0 # 5' --> 3' X U U G G YM # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U U G G YA # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U U G G YC # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U U G G YG # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 1.6 1.6 1.6 1.6 1.6 A 1.6 1.6 1.6 1.6 1.6 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 1.6 1.6 1.6 U 2.7 2.7 2.7 2.7 2.0 # 5' --> 3' X U U G G YU # 3' <-- 5' # Y # ---------------------------- M A C G U # ---------------------------- M 2.7 2.7 2.7 1.6 2.7 A 2.7 2.7 2.7 1.6 2.7 C 2.7 2.7 2.7 2.7 2.7 G 1.6 1.6 2.7 1.6 2.7 U 2.0 2.0 2.0 2.0 2.0