#Data tables for asymmetric interior loops of size 3 #enthalpy (energies) at 37 degrees for DNA #Data Arrangement: #For the 4x4 tables, each starting pair needs its own table. #This is the AA table: # 5' --> 3' # X # A A # T T # YA # 3' <-- 5' # Y-> # ---------------------------- # (X) A C G U # | ---------------------------- # V # (A) 31.8 31.8 29.6 31.8 # (C) 29.3 29.3 29.3 29.3 # (G) 20.7 20.7 20.7 20.7 # (U) 29.3 29.3 29.3 14.1 #An energy of "." is "infinity," i.e. not allowed. # 5' --> 3' X A A T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.8 31.8 29.6 31.8 C 29.3 29.3 29.3 29.3 G 20.7 20.7 20.7 20.7 U 29.3 29.3 29.3 14.1 # 5' --> 3' X A C T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 29.8 27.8 29.8 C 23.0 23.0 23.0 20.2 G 23.4 23.4 13.9 23.4 U 23.0 23.0 23.0 19.4 # 5' --> 3' X A G T C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.9 23.9 12.6 23.9 C 24.2 24.2 24.2 14.0 G 16.7 16.7 16.7 16.7 U 24.2 6.6 24.2 11.4 # 5' --> 3' X A T T A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.8 28.7 26.0 23.8 C 28.7 28.7 28.7 23.2 G 26.0 26.0 26.0 26.0 U 28.7 23.2 28.7 28.7 # 5' --> 3' X A G T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.9 23.9 12.6 23.9 C 24.2 24.2 24.2 14.0 G 16.7 16.7 16.7 16.7 U 24.2 6.6 24.2 11.4 # 5' --> 3' X A T T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 29.8 27.8 29.8 C 23.0 23.0 23.0 20.2 G 23.4 23.4 13.9 23.4 U 23.0 23.0 23.0 19.4 # 5' --> 3' X A A T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.8 20.4 29.6 20.4 C 29.3 33.6 29.3 17.3 G 20.7 20.4 20.5 20.4 U 29.3 22.4 29.3 14.1 # 5' --> 3' X A C T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.8 29.8 27.8 29.8 C 23.0 31.7 23.0 20.2 G 23.4 29.8 13.9 29.8 U 23.0 30.5 23.0 19.4 # 5' --> 3' X A G T C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 12.6 22.8 C 24.2 21.5 24.2 14.0 G 16.7 22.8 9.0 22.8 U 6.6 6.6 6.6 6.6 # 5' --> 3' X A T T A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.7 28.7 26.0 28.7 C 28.7 26.4 28.7 23.2 G 26.0 28.7 23.0 28.7 U 23.2 23.2 23.2 23.2 # 5' --> 3' X A G T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 12.6 22.8 C 24.2 21.5 24.2 14.0 G 16.7 22.8 9.0 22.8 U 6.6 6.6 6.6 6.6 # 5' --> 3' X A T T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.8 29.8 27.8 29.8 C 23.0 31.7 23.0 20.2 G 23.4 29.8 13.9 29.8 U 23.0 30.5 23.0 19.4 # 5' --> 3' X A A T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.6 29.6 29.6 29.6 C 29.3 29.3 29.3 29.3 G 20.7 20.5 20.5 20.5 U 29.3 29.3 29.3 14.1 # 5' --> 3' X A C T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 27.8 27.8 27.8 27.8 C 23.0 23.0 23.0 20.2 G 13.9 13.9 13.9 13.9 U 23.0 23.0 23.0 19.4 # 5' --> 3' X A G T C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 12.6 12.6 12.6 12.6 C 24.2 24.2 24.2 14.0 G 16.7 9.0 9.0 9.0 U 24.2 6.6 24.2 11.4 # 5' --> 3' X A T T A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 26.0 26.0 26.0 26.0 C 28.7 28.7 28.7 23.2 G 26.0 23.0 23.0 23.0 U 28.7 23.2 28.7 28.7 # 5' --> 3' X A G T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 12.6 12.6 12.6 12.6 C 24.2 24.2 24.2 14.0 G 16.7 9.0 9.0 9.0 U 24.2 6.6 24.2 11.4 # 5' --> 3' X A T T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 27.8 27.8 27.8 27.8 C 23.0 23.0 23.0 20.2 G 13.9 13.9 13.9 13.9 U 23.0 23.0 23.0 19.4 # 5' --> 3' X A A T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.8 20.4 29.6 20.4 C 17.3 17.3 17.3 17.3 G 20.7 20.4 20.5 20.4 U 14.1 14.1 14.1 14.1 # 5' --> 3' X A C T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.8 29.8 27.8 29.8 C 20.2 20.2 20.2 20.2 G 23.4 29.8 13.9 29.8 U 19.4 19.4 19.4 19.4 # 5' --> 3' X A G T C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 12.6 22.8 C 14.0 14.0 14.0 14.0 G 16.7 22.8 9.0 22.8 U 11.4 6.6 11.4 11.4 # 5' --> 3' X A T T A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.7 28.7 26.0 28.7 C 23.2 23.2 23.2 23.2 G 26.0 28.7 23.0 28.7 U 28.7 23.2 28.7 24.6 # 5' --> 3' X A G T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 12.6 22.8 C 14.0 14.0 14.0 14.0 G 16.7 22.8 9.0 22.8 U 11.4 6.6 11.4 11.4 # 5' --> 3' X A T T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.8 29.8 27.8 29.8 C 20.2 20.2 20.2 20.2 G 23.4 29.8 13.9 29.8 U 19.4 19.4 19.4 19.4 # 5' --> 3' X C A G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 28.9 30.2 28.9 C 28.5 28.5 28.5 19.0 G 25.8 25.8 17.8 25.8 U 28.5 21.9 28.5 19.6 # 5' --> 3' X C C G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 23.5 20.2 23.5 C 28.2 28.2 28.2 20.8 G 22.8 22.8 18.0 22.8 U 28.2 19.4 28.2 21.0 # 5' --> 3' X C G G C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 22.9 25.0 22.9 C 24.0 24.0 24.0 20.5 G 25.0 25.0 25.0 25.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X C T G A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.9 24.2 16.7 24.2 C 22.8 22.8 22.8 6.6 G 12.6 12.6 9.0 12.6 U 22.8 14.0 22.8 11.4 # 5' --> 3' X C G G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 22.9 25.0 22.9 C 24.0 24.0 24.0 20.5 G 25.0 25.0 25.0 25.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X C T G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 23.5 20.2 23.5 C 28.2 28.2 28.2 20.8 G 22.8 22.8 18.0 22.8 U 28.2 19.4 28.2 21.0 # 5' --> 3' X C A G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 32.1 30.2 32.1 C 28.5 24.8 28.5 19.0 G 25.8 32.1 17.8 32.1 U 21.9 21.9 21.9 19.6 # 5' --> 3' X C C G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 28.2 26.4 28.2 20.8 G 22.8 23.5 18.0 23.5 U 19.4 19.4 19.4 19.4 # 5' --> 3' X C G G C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 24.0 23.0 24.0 20.5 G 25.0 24.0 19.0 24.0 U 20.5 20.5 20.5 16.2 # 5' --> 3' X C T G A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 24.2 24.2 16.7 24.2 C 22.8 21.5 22.8 6.6 G 12.6 24.2 9.0 24.2 U 14.0 14.0 14.0 11.4 # 5' --> 3' X C G G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 24.0 23.0 24.0 20.5 G 25.0 24.0 19.0 24.0 U 20.5 20.5 20.5 16.2 # 5' --> 3' X C T G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 28.2 26.4 28.2 20.8 G 22.8 23.5 18.0 23.5 U 19.4 19.4 19.4 19.4 # 5' --> 3' X C A G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 30.2 30.2 30.2 30.2 C 28.5 28.5 28.5 19.0 G 17.8 17.8 17.8 17.8 U 28.5 21.9 28.5 19.6 # 5' --> 3' X C C G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 20.2 20.2 20.2 20.2 C 28.2 28.2 28.2 20.8 G 18.0 18.0 18.0 18.0 U 28.2 19.4 28.2 21.0 # 5' --> 3' X C G G C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.0 25.0 25.0 25.0 C 24.0 24.0 24.0 20.5 G 25.0 19.0 19.0 19.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X C T G A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 16.7 16.7 16.7 16.7 C 22.8 22.8 22.8 6.6 G 9.0 9.0 9.0 9.0 U 22.8 14.0 22.8 11.4 # 5' --> 3' X C G G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.0 25.0 25.0 25.0 C 24.0 24.0 24.0 20.5 G 25.0 19.0 19.0 19.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X C T G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 20.2 20.2 20.2 20.2 C 28.2 28.2 28.2 20.8 G 18.0 18.0 18.0 18.0 U 28.2 19.4 28.2 21.0 # 5' --> 3' X C A G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 32.1 30.2 32.1 C 19.0 19.0 19.0 19.0 G 25.8 32.1 17.8 32.1 U 19.6 19.6 19.6 19.6 # 5' --> 3' X C C G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 20.8 20.8 20.8 20.8 G 22.8 23.5 18.0 23.5 U 21.0 21.0 21.0 21.0 # 5' --> 3' X C G G C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 20.5 20.5 20.5 20.5 G 25.0 24.0 19.0 24.0 U 16.2 16.2 16.2 16.2 # 5' --> 3' X C T G A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 24.2 24.2 16.7 24.2 C 6.6 6.6 6.6 6.6 G 12.6 24.2 9.0 24.2 U 11.4 11.4 11.4 11.4 # 5' --> 3' X C G G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 20.5 20.5 20.5 20.5 G 25.0 24.0 19.0 24.0 U 16.2 16.2 16.2 16.2 # 5' --> 3' X C T G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 20.8 20.8 20.8 20.8 G 22.8 23.5 18.0 23.5 U 21.0 21.0 21.0 21.0 # 5' --> 3' X G A C T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 17.5 17.5 17.5 C 23.1 23.1 23.1 23.1 G 25.8 25.8 25.8 25.8 U 23.1 23.1 23.1 8.9 # 5' --> 3' X G C C G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 21.5 21.3 21.5 C 22.8 22.8 22.8 22.8 G 21.3 21.3 16.1 21.3 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G G C C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 18.3 22.8 18.3 C 23.5 23.5 23.5 23.5 G 20.2 20.2 20.2 20.2 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T C A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 23.0 23.4 23.0 C 29.8 29.8 29.8 29.8 G 27.8 27.8 13.9 27.8 U 29.8 20.2 29.8 19.4 # 5' --> 3' X G G C T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 18.3 22.8 18.3 C 23.5 23.5 23.5 23.5 G 20.2 20.2 20.2 20.2 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T C G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 21.5 21.3 21.5 C 22.8 22.8 22.8 22.8 G 21.3 21.3 16.1 21.3 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G A C T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 32.1 30.2 32.1 C 23.1 31.8 23.1 18.5 G 25.8 32.1 22.3 32.1 U 23.1 22.6 23.1 8.9 # 5' --> 3' X G C C G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 24.9 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 18.3 # 5' --> 3' X G G C C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 26.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 20.8 23.5 21.0 # 5' --> 3' X G T C A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.0 23.0 23.4 23.0 C 29.8 31.7 29.8 30.5 G 27.8 23.0 13.9 23.0 U 20.2 20.2 20.2 20.2 # 5' --> 3' X G G C T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 26.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 20.8 23.5 21.0 # 5' --> 3' X G T C G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 24.9 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 18.3 # 5' --> 3' X G A C T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 30.2 30.2 30.2 30.2 C 23.1 23.1 23.1 23.1 G 25.8 22.3 22.3 22.3 U 23.1 23.1 23.1 8.9 # 5' --> 3' X G C C G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.3 21.3 21.3 21.3 C 22.8 22.8 22.8 22.8 G 16.1 16.1 16.1 16.1 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G G C C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 22.8 22.8 C 23.5 23.5 23.5 23.5 G 20.2 18.0 18.0 18.0 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T C A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.4 23.4 23.4 23.4 C 29.8 29.8 29.8 29.8 G 13.9 13.9 13.9 13.9 U 29.8 20.2 29.8 19.4 # 5' --> 3' X G G C T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 22.8 22.8 C 23.5 23.5 23.5 23.5 G 20.2 18.0 18.0 18.0 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T C G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.3 21.3 21.3 21.3 C 22.8 22.8 22.8 22.8 G 16.1 16.1 16.1 16.1 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G A C T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 32.1 30.2 32.1 C 23.1 18.5 23.1 18.5 G 25.8 32.1 22.3 32.1 U 8.9 8.9 8.9 8.9 # 5' --> 3' X G C C G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 18.3 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 19.2 # 5' --> 3' X G G C C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 19.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 21.0 23.5 21.0 # 5' --> 3' X G T C A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.0 23.0 23.4 23.0 C 29.8 30.5 29.8 30.5 G 27.8 23.0 13.9 23.0 U 19.4 19.4 19.4 19.4 # 5' --> 3' X G G C T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 19.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 21.0 23.5 21.0 # 5' --> 3' X G T C G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 18.3 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 19.2 # 5' --> 3' X T A A T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.0 31.0 30.8 31.0 C 33.2 33.2 33.2 21.4 G 30.8 30.8 30.8 30.8 U 33.2 21.4 33.2 25.1 # 5' --> 3' X T C A G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 17.5 25.8 17.5 C 32.1 32.1 32.1 32.1 G 30.2 30.2 22.3 30.2 U 32.1 18.5 32.1 8.9 # 5' --> 3' X T G A C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 28.9 25.8 28.9 C 32.1 32.1 32.1 21.9 G 30.2 30.2 17.8 30.2 U 32.1 19.0 32.1 19.6 # 5' --> 3' X T T A A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.8 29.3 20.7 29.3 C 20.4 20.4 20.4 22.4 G 29.6 29.6 20.5 29.6 U 20.4 17.3 20.4 14.1 # 5' --> 3' X T G A T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 28.9 25.8 28.9 C 32.1 32.1 32.1 21.9 G 30.2 30.2 17.8 30.2 U 32.1 19.0 32.1 19.6 # 5' --> 3' X T T A G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 17.5 25.8 17.5 C 32.1 32.1 32.1 32.1 G 30.2 30.2 22.3 30.2 U 32.1 18.5 32.1 8.9 # 5' --> 3' X T A A T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.0 33.2 30.8 33.2 C 33.2 36.3 33.2 21.4 G 30.8 33.2 27.3 33.2 U 21.4 21.4 21.4 21.4 # 5' --> 3' X T C A G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 23.1 25.8 23.1 C 32.1 31.8 32.1 31.8 G 30.2 23.1 22.3 23.1 U 18.5 18.5 18.5 8.9 # 5' --> 3' X T G A C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.5 28.5 25.8 28.5 C 32.1 24.8 32.1 21.9 G 30.2 28.5 17.8 28.5 U 19.0 19.0 19.0 19.6 # 5' --> 3' X T T A A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.3 29.3 20.7 29.3 C 20.4 33.6 20.4 22.4 G 29.6 29.3 20.5 29.3 U 17.3 17.3 17.3 14.1 # 5' --> 3' X T G A T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.5 28.5 25.8 28.5 C 32.1 24.8 32.1 21.9 G 30.2 28.5 17.8 28.5 U 19.0 19.0 19.0 19.6 # 5' --> 3' X T T A G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 23.1 25.8 23.1 C 32.1 31.8 32.1 31.8 G 30.2 23.1 22.3 23.1 U 18.5 18.5 18.5 8.9 # 5' --> 3' X T A A T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 30.8 30.8 30.8 30.8 C 33.2 33.2 33.2 21.4 G 30.8 27.3 27.3 27.3 U 33.2 21.4 33.2 25.1 # 5' --> 3' X T C A G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.8 25.8 25.8 25.8 C 32.1 32.1 32.1 32.1 G 22.3 22.3 22.3 22.3 U 32.1 18.5 32.1 8.9 # 5' --> 3' X T G A C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.8 25.8 25.8 25.8 C 32.1 32.1 32.1 21.9 G 17.8 17.8 17.8 17.8 U 32.1 19.0 32.1 19.6 # 5' --> 3' X T T A A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 20.7 20.7 20.7 20.7 C 20.4 20.4 20.4 22.4 G 20.5 20.5 20.5 20.5 U 20.4 17.3 20.4 14.1 # 5' --> 3' X T G A T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.8 25.8 25.8 25.8 C 32.1 32.1 32.1 21.9 G 17.8 17.8 17.8 17.8 U 32.1 19.0 32.1 19.6 # 5' --> 3' X T T A G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.8 25.8 25.8 25.8 C 32.1 32.1 32.1 32.1 G 22.3 22.3 22.3 22.3 U 32.1 18.5 32.1 8.9 # 5' --> 3' X T A A T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 31.0 33.2 30.8 33.2 C 21.4 21.4 21.4 21.4 G 30.8 33.2 27.3 33.2 U 25.1 21.4 25.1 25.1 # 5' --> 3' X T C A G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 23.1 25.8 23.1 C 32.1 22.6 32.1 22.6 G 30.2 23.1 22.3 23.1 U 8.9 8.9 8.9 8.9 # 5' --> 3' X T G A C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.5 28.5 25.8 28.5 C 21.9 21.9 21.9 21.9 G 30.2 28.5 17.8 28.5 U 19.6 19.6 19.6 19.6 # 5' --> 3' X T T A A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 29.3 29.3 20.7 29.3 C 22.4 22.4 22.4 22.4 G 29.6 29.3 20.5 29.3 U 14.1 14.1 14.1 14.1 # 5' --> 3' X T G A T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.5 28.5 25.8 28.5 C 21.9 21.9 21.9 21.9 G 30.2 28.5 17.8 28.5 U 19.6 19.6 19.6 19.6 # 5' --> 3' X T T A G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 23.1 25.8 23.1 C 32.1 22.6 32.1 22.6 G 30.2 23.1 22.3 23.1 U 8.9 8.9 8.9 8.9 # 5' --> 3' X G A T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 17.5 17.5 17.5 C 23.1 23.1 23.1 23.1 G 25.8 25.8 25.8 25.8 U 23.1 23.1 23.1 8.9 # 5' --> 3' X G C T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 21.5 21.3 21.5 C 22.8 22.8 22.8 22.8 G 21.3 21.3 16.1 21.3 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G G T C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 18.3 22.8 18.3 C 23.5 23.5 23.5 23.5 G 20.2 20.2 20.2 20.2 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T T A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 23.0 23.4 23.0 C 29.8 29.8 29.8 29.8 G 27.8 27.8 13.9 27.8 U 29.8 20.2 29.8 19.4 # 5' --> 3' X G G T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 18.3 22.8 18.3 C 23.5 23.5 23.5 23.5 G 20.2 20.2 20.2 20.2 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 21.5 21.3 21.5 C 22.8 22.8 22.8 22.8 G 21.3 21.3 16.1 21.3 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G A T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 32.1 30.2 32.1 C 23.1 31.8 23.1 18.5 G 25.8 32.1 22.3 32.1 U 23.1 22.6 23.1 8.9 # 5' --> 3' X G C T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 24.9 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 18.3 # 5' --> 3' X G G T C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 26.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 20.8 23.5 21.0 # 5' --> 3' X G T T A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.0 23.0 23.4 23.0 C 29.8 31.7 29.8 30.5 G 27.8 23.0 13.9 23.0 U 20.2 20.2 20.2 20.2 # 5' --> 3' X G G T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 26.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 20.8 23.5 21.0 # 5' --> 3' X G T T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 24.9 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 18.3 # 5' --> 3' X G A T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 30.2 30.2 30.2 30.2 C 23.1 23.1 23.1 23.1 G 25.8 22.3 22.3 22.3 U 23.1 23.1 23.1 8.9 # 5' --> 3' X G C T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.3 21.3 21.3 21.3 C 22.8 22.8 22.8 22.8 G 16.1 16.1 16.1 16.1 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G G T C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 22.8 22.8 C 23.5 23.5 23.5 23.5 G 20.2 18.0 18.0 18.0 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T T A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.4 23.4 23.4 23.4 C 29.8 29.8 29.8 29.8 G 13.9 13.9 13.9 13.9 U 29.8 20.2 29.8 19.4 # 5' --> 3' X G G T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.8 22.8 22.8 22.8 C 23.5 23.5 23.5 23.5 G 20.2 18.0 18.0 18.0 U 23.5 23.5 23.5 23.5 # 5' --> 3' X G T T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.3 21.3 21.3 21.3 C 22.8 22.8 22.8 22.8 G 16.1 16.1 16.1 16.1 U 22.8 22.8 22.8 22.8 # 5' --> 3' X G A T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 17.5 32.1 30.2 32.1 C 23.1 18.5 23.1 18.5 G 25.8 32.1 22.3 32.1 U 8.9 8.9 8.9 8.9 # 5' --> 3' X G C T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 18.3 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 19.2 # 5' --> 3' X G G T C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 19.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 21.0 23.5 21.0 # 5' --> 3' X G T T A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.0 23.0 23.4 23.0 C 29.8 30.5 29.8 30.5 G 27.8 23.0 13.9 23.0 U 19.4 19.4 19.4 19.4 # 5' --> 3' X G G T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 28.2 22.8 28.2 C 23.5 19.4 23.5 19.4 G 20.2 28.2 18.0 28.2 U 23.5 21.0 23.5 21.0 # 5' --> 3' X G T T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 21.5 22.8 21.3 22.8 C 22.8 18.3 22.8 18.3 G 21.3 22.8 16.1 22.8 U 22.8 18.3 22.8 19.2 # 5' --> 3' X T A G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 28.9 30.2 28.9 C 28.5 28.5 28.5 19.0 G 25.8 25.8 17.8 25.8 U 28.5 21.9 28.5 19.6 # 5' --> 3' X T C G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 23.5 20.2 23.5 C 28.2 28.2 28.2 20.8 G 22.8 22.8 18.0 22.8 U 28.2 19.4 28.2 21.0 # 5' --> 3' X T G G C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 22.9 25.0 22.9 C 24.0 24.0 24.0 20.5 G 25.0 25.0 25.0 25.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X T T G A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.9 24.2 16.7 24.2 C 22.8 22.8 22.8 6.6 G 12.6 12.6 9.0 12.6 U 22.8 14.0 22.8 11.4 # 5' --> 3' X T G G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 22.9 25.0 22.9 C 24.0 24.0 24.0 20.5 G 25.0 25.0 25.0 25.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X T T G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 18.3 23.5 20.2 23.5 C 28.2 28.2 28.2 20.8 G 22.8 22.8 18.0 22.8 U 28.2 19.4 28.2 21.0 # 5' --> 3' X T A G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 32.1 30.2 32.1 C 28.5 24.8 28.5 19.0 G 25.8 32.1 17.8 32.1 U 21.9 21.9 21.9 19.6 # 5' --> 3' X T C G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 28.2 26.4 28.2 20.8 G 22.8 23.5 18.0 23.5 U 19.4 19.4 19.4 19.4 # 5' --> 3' X T G G C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 24.0 23.0 24.0 20.5 G 25.0 24.0 19.0 24.0 U 20.5 20.5 20.5 16.2 # 5' --> 3' X T T G A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 24.2 24.2 16.7 24.2 C 22.8 21.5 22.8 6.6 G 12.6 24.2 9.0 24.2 U 14.0 14.0 14.0 11.4 # 5' --> 3' X T G G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 24.0 23.0 24.0 20.5 G 25.0 24.0 19.0 24.0 U 20.5 20.5 20.5 16.2 # 5' --> 3' X T T G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 28.2 26.4 28.2 20.8 G 22.8 23.5 18.0 23.5 U 19.4 19.4 19.4 19.4 # 5' --> 3' X T A G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 30.2 30.2 30.2 30.2 C 28.5 28.5 28.5 19.0 G 17.8 17.8 17.8 17.8 U 28.5 21.9 28.5 19.6 # 5' --> 3' X T C G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 20.2 20.2 20.2 20.2 C 28.2 28.2 28.2 20.8 G 18.0 18.0 18.0 18.0 U 28.2 19.4 28.2 21.0 # 5' --> 3' X T G G C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.0 25.0 25.0 25.0 C 24.0 24.0 24.0 20.5 G 25.0 19.0 19.0 19.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X T T G A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 16.7 16.7 16.7 16.7 C 22.8 22.8 22.8 6.6 G 9.0 9.0 9.0 9.0 U 22.8 14.0 22.8 11.4 # 5' --> 3' X T G G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 25.0 25.0 25.0 25.0 C 24.0 24.0 24.0 20.5 G 25.0 19.0 19.0 19.0 U 24.0 20.5 24.0 16.2 # 5' --> 3' X T T G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 20.2 20.2 20.2 20.2 C 28.2 28.2 28.2 20.8 G 18.0 18.0 18.0 18.0 U 28.2 19.4 28.2 21.0 # 5' --> 3' X T A G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 28.9 32.1 30.2 32.1 C 19.0 19.0 19.0 19.0 G 25.8 32.1 17.8 32.1 U 19.6 19.6 19.6 19.6 # 5' --> 3' X T C G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 20.8 20.8 20.8 20.8 G 22.8 23.5 18.0 23.5 U 21.0 21.0 21.0 21.0 # 5' --> 3' X T G G C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 20.5 20.5 20.5 20.5 G 25.0 24.0 19.0 24.0 U 16.2 16.2 16.2 16.2 # 5' --> 3' X T T G A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 24.2 24.2 16.7 24.2 C 6.6 6.6 6.6 6.6 G 12.6 24.2 9.0 24.2 U 11.4 11.4 11.4 11.4 # 5' --> 3' X T G G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 22.9 24.0 25.0 24.0 C 20.5 20.5 20.5 20.5 G 25.0 24.0 19.0 24.0 U 16.2 16.2 16.2 16.2 # 5' --> 3' X T T G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 23.5 23.5 20.2 23.5 C 20.8 20.8 20.8 20.8 G 22.8 23.5 18.0 23.5 U 21.0 21.0 21.0 21.0