#Data tables for asymmetric interior loops of size 3 #Free energies at 37 degrees for DNA #Data Arrangement: #For the 4x4 tables, each starting pair needs its own table. #This is the AA table: # 5' --> 3' # X # A A # T T # YA # 3' <-- 5' # Y-> # ---------------------------- # (X) A C G U # | ---------------------------- # V # (A) 1.8 2.0 1.9 2.5 # (C) 2.1 2.3 2.2 2.2 # (G) 1.9 2.3 1.9 2.5 # (U) 3.1 2.7 3.1 2.5 #An energy of "." is "infinity," i.e. not allowed. # 5' --> 3' X A A T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.0 1.9 2.5 C 2.1 2.3 2.2 2.2 G 1.9 2.3 1.9 2.5 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A C T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 1.5 1.4 2.0 C 1.8 2.0 1.9 1.9 G 1.5 1.9 1.5 2.1 U 2.6 2.2 2.6 2.0 # 5' --> 3' X A G T C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.6 1.5 2.1 C 1.9 2.1 2.0 2.0 G 1.6 2.0 1.6 2.2 U 2.7 2.3 2.7 2.1 # 5' --> 3' X A T T A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.7 1.9 1.8 2.4 C 2.1 2.3 2.2 2.2 G 1.9 2.3 1.9 2.5 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A G T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.1 2.0 2.6 C 2.4 2.6 2.5 2.5 G 2.0 2.4 2.0 2.6 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A T T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.1 2.0 2.6 C 2.4 2.6 2.5 2.5 G 2.0 2.4 2.0 2.6 U 2.9 2.5 2.9 2.3 # 5' --> 3' X A A T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.1 2.0 2.6 C 2.3 2.5 2.4 2.4 G 2.0 2.4 2.0 2.6 U 2.7 2.3 2.7 2.1 # 5' --> 3' X A C T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.8 1.7 2.3 C 2.0 2.2 2.1 2.1 G 1.2 1.6 1.2 1.8 U 2.4 2.0 2.4 1.8 # 5' --> 3' X A G T C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.7 1.9 1.8 2.4 C 2.1 2.3 2.2 2.2 G 1.7 2.1 1.7 2.3 U 2.4 2.0 2.4 1.8 # 5' --> 3' X A T T A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.1 2.0 2.6 C 2.3 2.5 2.4 2.4 G 2.1 2.5 2.1 2.7 U 2.7 2.3 2.7 2.1 # 5' --> 3' X A G T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.2 2.4 2.3 2.9 C 2.4 2.6 2.5 2.5 G 2.2 2.6 2.2 2.8 U 2.9 2.5 2.9 2.3 # 5' --> 3' X A T T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.2 2.4 2.3 2.9 C 2.4 2.6 2.5 2.5 G 2.1 2.5 2.1 2.7 U 2.9 2.5 2.9 2.3 # 5' --> 3' X A A T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.0 1.9 2.5 C 2.6 2.8 2.7 2.7 G 1.9 2.3 1.9 2.5 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A C T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.6 1.5 2.1 C 1.8 2.0 1.9 1.9 G 1.5 1.9 1.5 2.1 U 2.8 2.4 2.8 2.2 # 5' --> 3' X A G T C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.7 1.6 2.2 C 1.5 1.7 1.6 1.6 G 1.6 2.0 1.6 2.2 U 2.6 2.2 2.6 2.0 # 5' --> 3' X A T T A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.0 1.9 2.5 C 2.4 2.6 2.5 2.5 G 1.9 2.3 1.9 2.5 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A G T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.1 2.0 2.6 C 2.1 2.3 2.2 2.2 G 2.0 2.4 2.0 2.6 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A T T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.1 2.0 2.6 C 2.2 2.4 2.3 2.3 G 2.0 2.4 2.0 2.6 U 3.1 2.7 3.1 2.5 # 5' --> 3' X A A T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.6 2.5 3.1 C 2.2 2.4 2.3 2.3 G 2.4 2.8 2.4 3.0 U 2.5 2.1 2.5 1.9 # 5' --> 3' X A C T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.2 2.1 2.7 C 1.9 2.1 2.0 2.0 G 2.1 2.5 2.1 2.7 U 2.2 1.8 2.2 1.6 # 5' --> 3' X A G T C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.2 2.4 2.3 2.9 C 1.9 2.1 2.0 2.0 G 2.1 2.5 2.1 2.7 U 2.2 1.8 2.2 1.6 # 5' --> 3' X A T T A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.6 2.5 3.1 C 2.2 2.4 2.3 2.3 G 2.5 2.9 2.5 3.1 U 2.5 2.1 2.5 1.9 # 5' --> 3' X A G T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.6 2.5 3.1 C 2.4 2.6 2.5 2.5 G 2.5 2.9 2.5 3.1 U 2.9 2.5 2.9 2.3 # 5' --> 3' X A T T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.6 2.5 3.1 C 2.4 2.6 2.5 2.5 G 2.5 2.9 2.5 3.1 U 2.9 2.5 2.9 2.3 # 5' --> 3' X C A G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 1.9 2.1 1.8 1.9 G 1.6 1.4 1.6 2.0 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C C G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.0 1.3 1.1 1.6 C 1.6 1.8 1.5 1.6 G 1.2 1.0 1.2 1.6 U 2.4 1.9 2.2 1.7 # 5' --> 3' X C G G C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.1 1.4 1.2 1.7 C 1.7 1.9 1.6 1.7 G 1.3 1.1 1.3 1.7 U 2.5 2.0 2.3 1.8 # 5' --> 3' X C T G A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.7 1.5 2.0 C 1.9 2.1 1.8 1.9 G 1.6 1.4 1.6 2.0 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C G G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 2.2 2.4 2.1 2.2 G 1.7 1.5 1.7 2.1 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C T G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 2.2 2.4 2.1 2.2 G 1.7 1.5 1.7 2.1 U 2.7 2.2 2.5 2.0 # 5' --> 3' X C A G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 2.1 2.3 2.0 2.1 G 1.7 1.5 1.7 2.1 U 2.5 2.0 2.3 1.8 # 5' --> 3' X C C G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 1.6 1.4 1.9 C 1.8 2.0 1.7 1.8 G 0.9 0.7 0.9 1.3 U 2.2 1.7 2.0 1.5 # 5' --> 3' X C G G C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.7 1.5 2.0 C 1.9 2.1 1.8 1.9 G 1.4 1.2 1.4 1.8 U 2.2 1.7 2.0 1.5 # 5' --> 3' X C T G A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 2.1 2.3 2.0 2.1 G 1.8 1.6 1.8 2.2 U 2.5 2.0 2.3 1.8 # 5' --> 3' X C G G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 2.0 2.5 C 2.2 2.4 2.1 2.2 G 1.9 1.7 1.9 2.3 U 2.7 2.2 2.5 2.0 # 5' --> 3' X C T G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 2.0 2.5 C 2.2 2.4 2.1 2.2 G 1.8 1.6 1.8 2.2 U 2.7 2.2 2.5 2.0 # 5' --> 3' X C A G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 2.4 2.6 2.3 2.4 G 1.6 1.4 1.6 2.0 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C C G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.1 1.4 1.2 1.7 C 1.6 1.8 1.5 1.6 G 1.2 1.0 1.2 1.6 U 2.6 2.1 2.4 1.9 # 5' --> 3' X C G G C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.2 1.5 1.3 1.8 C 1.3 1.5 1.2 1.3 G 1.3 1.1 1.3 1.7 U 2.4 1.9 2.2 1.7 # 5' --> 3' X C T G A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 2.2 2.4 2.1 2.2 G 1.6 1.4 1.6 2.0 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C G G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 1.9 2.1 1.8 1.9 G 1.7 1.5 1.7 2.1 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C T G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 2.0 2.2 1.9 2.0 G 1.7 1.5 1.7 2.1 U 2.9 2.4 2.7 2.2 # 5' --> 3' X C A G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.2 2.7 C 2.0 2.2 1.9 2.0 G 2.1 1.9 2.1 2.5 U 2.3 1.8 2.1 1.6 # 5' --> 3' X C C G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.7 2.0 1.8 2.3 C 1.7 1.9 1.6 1.7 G 1.8 1.6 1.8 2.2 U 2.0 1.5 1.8 1.3 # 5' --> 3' X C G G C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 2.0 2.5 C 1.7 1.9 1.6 1.7 G 1.8 1.6 1.8 2.2 U 2.0 1.5 1.8 1.3 # 5' --> 3' X C T G A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.2 2.7 C 2.0 2.2 1.9 2.0 G 2.2 2.0 2.2 2.6 U 2.3 1.8 2.1 1.6 # 5' --> 3' X C G G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.2 2.7 C 2.2 2.4 2.1 2.2 G 2.2 2.0 2.2 2.6 U 2.7 2.2 2.5 2.0 # 5' --> 3' X C T G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.2 2.7 C 2.2 2.4 2.1 2.2 G 2.2 2.0 2.2 2.6 U 2.7 2.2 2.5 2.0 # 5' --> 3' X G A C T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.7 1.5 2.0 C 1.8 2.0 1.3 1.9 G 1.5 1.7 1.5 2.2 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G C C G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.9 1.2 1.0 1.5 C 1.5 1.7 1.0 1.6 G 1.1 1.3 1.1 1.8 U 2.2 1.9 2.2 1.7 # 5' --> 3' X G G C C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.0 1.3 1.1 1.6 C 1.6 1.8 1.1 1.7 G 1.2 1.4 1.2 1.9 U 2.3 2.0 2.3 1.8 # 5' --> 3' X G T C A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 1.6 1.4 1.9 C 1.8 2.0 1.3 1.9 G 1.5 1.7 1.5 2.2 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G G C T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 2.1 2.3 1.6 2.2 G 1.6 1.8 1.6 2.3 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G T C G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 2.1 2.3 1.6 2.2 G 1.6 1.8 1.6 2.3 U 2.5 2.2 2.5 2.0 # 5' --> 3' X G A C T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 2.0 2.2 1.5 2.1 G 1.6 1.8 1.6 2.3 U 2.3 2.0 2.3 1.8 # 5' --> 3' X G C C G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.2 1.5 1.3 1.8 C 1.7 1.9 1.2 1.8 G 0.8 1.0 0.8 1.5 U 2.0 1.7 2.0 1.5 # 5' --> 3' X G G C C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 1.6 1.4 1.9 C 1.8 2.0 1.3 1.9 G 1.3 1.5 1.3 2.0 U 2.0 1.7 2.0 1.5 # 5' --> 3' X G T C A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 2.0 2.2 1.5 2.1 G 1.7 1.9 1.7 2.4 U 2.3 2.0 2.3 1.8 # 5' --> 3' X G G C T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.1 1.9 2.4 C 2.1 2.3 1.6 2.2 G 1.8 2.0 1.8 2.5 U 2.5 2.2 2.5 2.0 # 5' --> 3' X G T C G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.1 1.9 2.4 C 2.1 2.3 1.6 2.2 G 1.7 1.9 1.7 2.4 U 2.5 2.2 2.5 2.0 # 5' --> 3' X G A C T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.7 1.5 2.0 C 2.3 2.5 1.8 2.4 G 1.5 1.7 1.5 2.2 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G C C G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.0 1.3 1.1 1.6 C 1.5 1.7 1.0 1.6 G 1.1 1.3 1.1 1.8 U 2.4 2.1 2.4 1.9 # 5' --> 3' X G G C C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.1 1.4 1.2 1.7 C 1.2 1.4 0.7 1.3 G 1.2 1.4 1.2 1.9 U 2.2 1.9 2.2 1.7 # 5' --> 3' X G T C A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.7 1.5 2.0 C 2.1 2.3 1.6 2.2 G 1.5 1.7 1.5 2.2 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G G C T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 1.8 2.0 1.3 1.9 G 1.6 1.8 1.6 2.3 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G T C G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.6 2.1 C 1.9 2.1 1.4 2.0 G 1.6 1.8 1.6 2.3 U 2.7 2.4 2.7 2.2 # 5' --> 3' X G A C T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.1 2.6 C 1.9 2.1 1.4 2.0 G 2.0 2.2 2.0 2.7 U 2.1 1.8 2.1 1.6 # 5' --> 3' X G C C G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.7 2.2 C 1.6 1.8 1.1 1.7 G 1.7 1.9 1.7 2.4 U 1.8 1.5 1.8 1.3 # 5' --> 3' X G G C C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.1 1.9 2.4 C 1.6 1.8 1.1 1.7 G 1.7 1.9 1.7 2.4 U 1.8 1.5 1.8 1.3 # 5' --> 3' X G T C A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.1 2.6 C 1.9 2.1 1.4 2.0 G 2.1 2.3 2.1 2.8 U 2.1 1.8 2.1 1.6 # 5' --> 3' X G G C T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.1 2.6 C 2.1 2.3 1.6 2.2 G 2.1 2.3 2.1 2.8 U 2.5 2.2 2.5 2.0 # 5' --> 3' X G T C G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.1 2.6 C 2.1 2.3 1.6 2.2 G 2.1 2.3 2.1 2.8 U 2.5 2.2 2.5 2.0 # 5' --> 3' X T A A T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.0 1.9 2.5 C 2.1 2.3 2.1 2.2 G 1.9 2.5 1.9 2.5 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T C A G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 1.5 1.4 2.0 C 1.8 2.0 1.8 1.9 G 1.5 2.1 1.5 2.1 U 2.6 2.2 2.5 2.0 # 5' --> 3' X T G A C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.6 1.5 2.1 C 1.9 2.1 1.9 2.0 G 1.6 2.2 1.6 2.2 U 2.7 2.3 2.6 2.1 # 5' --> 3' X T T A A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 1.9 1.8 2.4 C 2.1 2.3 2.1 2.2 G 1.9 2.5 1.9 2.5 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T G A T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.1 2.0 2.6 C 2.4 2.6 2.4 2.5 G 2.0 2.6 2.0 2.6 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T T A G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.1 2.0 2.6 C 2.4 2.6 2.4 2.5 G 2.0 2.6 2.0 2.6 U 2.9 2.5 2.8 2.3 # 5' --> 3' X T A A T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.1 2.0 2.6 C 2.3 2.5 2.3 2.4 G 2.0 2.6 2.0 2.6 U 2.7 2.3 2.6 2.1 # 5' --> 3' X T C A G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.7 1.8 1.7 2.3 C 2.0 2.2 2.0 2.1 G 1.2 1.8 1.2 1.8 U 2.4 2.0 2.3 1.8 # 5' --> 3' X T G A C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 1.9 1.8 2.4 C 2.1 2.3 2.1 2.2 G 1.7 2.3 1.7 2.3 U 2.4 2.0 2.3 1.8 # 5' --> 3' X T T A A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.1 2.0 2.6 C 2.3 2.5 2.3 2.4 G 2.1 2.7 2.1 2.7 U 2.7 2.3 2.6 2.1 # 5' --> 3' X T G A T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.3 2.4 2.3 2.9 C 2.4 2.6 2.4 2.5 G 2.2 2.8 2.2 2.8 U 2.9 2.5 2.8 2.3 # 5' --> 3' X T T A G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.3 2.4 2.3 2.9 C 2.4 2.6 2.4 2.5 G 2.1 2.7 2.1 2.7 U 2.9 2.5 2.8 2.3 # 5' --> 3' X T A A T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.0 1.9 2.5 C 2.6 2.8 2.6 2.7 G 1.9 2.5 1.9 2.5 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T C A G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.6 1.5 2.1 C 1.8 2.0 1.8 1.9 G 1.5 2.1 1.5 2.1 U 2.8 2.4 2.7 2.2 # 5' --> 3' X T G A C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.7 1.6 2.2 C 1.5 1.7 1.5 1.6 G 1.6 2.2 1.6 2.2 U 2.6 2.2 2.5 2.0 # 5' --> 3' X T T A A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.0 1.9 2.5 C 2.4 2.6 2.4 2.5 G 1.9 2.5 1.9 2.5 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T G A T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.1 2.0 2.6 C 2.1 2.3 2.1 2.2 G 2.0 2.6 2.0 2.6 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T T A G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.1 2.0 2.6 C 2.2 2.4 2.2 2.3 G 2.0 2.6 2.0 2.6 U 3.1 2.7 3.0 2.5 # 5' --> 3' X T A A T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.5 2.6 2.5 3.1 C 2.2 2.4 2.2 2.3 G 2.4 3.0 2.4 3.0 U 2.5 2.1 2.4 1.9 # 5' --> 3' X T C A G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.2 2.1 2.7 C 1.9 2.1 1.9 2.0 G 2.1 2.7 2.1 2.7 U 2.2 1.8 2.1 1.6 # 5' --> 3' X T G A C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.3 2.4 2.3 2.9 C 1.9 2.1 1.9 2.0 G 2.1 2.7 2.1 2.7 U 2.2 1.8 2.1 1.6 # 5' --> 3' X T T A A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.5 2.6 2.5 3.1 C 2.2 2.4 2.2 2.3 G 2.5 3.1 2.5 3.1 U 2.5 2.1 2.4 1.9 # 5' --> 3' X T G A T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.5 2.6 2.5 3.1 C 2.4 2.6 2.4 2.5 G 2.5 3.1 2.5 3.1 U 2.9 2.5 2.8 2.3 # 5' --> 3' X T T A G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.5 2.6 2.5 3.1 C 2.4 2.6 2.4 2.5 G 2.5 3.1 2.5 3.1 U 2.9 2.5 2.8 2.3 # 5' --> 3' X G A T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.0 2.3 C 2.4 2.4 2.2 2.4 G 2.0 2.1 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G C T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.5 1.8 C 2.1 2.1 1.9 2.1 G 1.6 1.7 1.6 2.1 U 2.6 2.4 2.6 2.4 # 5' --> 3' X G G T C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.6 1.9 C 2.2 2.2 2.0 2.2 G 1.7 1.8 1.7 2.2 U 2.7 2.5 2.7 2.5 # 5' --> 3' X G T T A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 1.9 2.2 C 2.4 2.4 2.2 2.4 G 2.0 2.1 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G G T T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.4 C 2.7 2.7 2.5 2.7 G 2.1 2.2 2.1 2.6 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G T T G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.4 C 2.7 2.7 2.5 2.7 G 2.1 2.2 2.1 2.6 U 2.9 2.7 2.9 2.7 # 5' --> 3' X G A T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.4 C 2.6 2.6 2.4 2.6 G 2.1 2.2 2.1 2.6 U 2.7 2.5 2.7 2.5 # 5' --> 3' X G C T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.1 1.8 2.1 C 2.3 2.3 2.1 2.3 G 1.3 1.4 1.3 1.8 U 2.4 2.2 2.4 2.2 # 5' --> 3' X G G T C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 1.9 2.2 C 2.4 2.4 2.2 2.4 G 1.8 1.9 1.8 2.3 U 2.4 2.2 2.4 2.2 # 5' --> 3' X G T T A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.4 C 2.6 2.6 2.4 2.6 G 2.2 2.3 2.2 2.7 U 2.7 2.5 2.7 2.5 # 5' --> 3' X G G T T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.7 2.4 2.7 C 2.7 2.7 2.5 2.7 G 2.3 2.4 2.3 2.8 U 2.9 2.7 2.9 2.7 # 5' --> 3' X G T T G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.7 2.4 2.7 C 2.7 2.7 2.5 2.7 G 2.2 2.3 2.2 2.7 U 2.9 2.7 2.9 2.7 # 5' --> 3' X G A T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.0 2.3 C 2.9 2.9 2.7 2.9 G 2.0 2.1 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G C T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.6 1.9 C 2.1 2.1 1.9 2.1 G 1.6 1.7 1.6 2.1 U 2.8 2.6 2.8 2.6 # 5' --> 3' X G G T C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.7 2.0 1.7 2.0 C 1.8 1.8 1.6 1.8 G 1.7 1.8 1.7 2.2 U 2.6 2.4 2.6 2.4 # 5' --> 3' X G T T A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.0 2.3 C 2.7 2.7 2.5 2.7 G 2.0 2.1 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G G T T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.4 C 2.4 2.4 2.2 2.4 G 2.1 2.2 2.1 2.6 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G T T G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.4 C 2.5 2.5 2.3 2.5 G 2.1 2.2 2.1 2.6 U 3.1 2.9 3.1 2.9 # 5' --> 3' X G A T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 2.9 C 2.5 2.5 2.3 2.5 G 2.5 2.6 2.5 3.0 U 2.5 2.3 2.5 2.3 # 5' --> 3' X G C T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.2 2.5 2.2 2.5 C 2.2 2.2 2.0 2.2 G 2.2 2.3 2.2 2.7 U 2.2 2.0 2.2 2.0 # 5' --> 3' X G G T C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.7 2.4 2.7 C 2.2 2.2 2.0 2.2 G 2.2 2.3 2.2 2.7 U 2.2 2.0 2.2 2.0 # 5' --> 3' X G T T A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 2.9 C 2.5 2.5 2.3 2.5 G 2.6 2.7 2.6 3.1 U 2.5 2.3 2.5 2.3 # 5' --> 3' X G G T T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 2.9 C 2.7 2.7 2.5 2.7 G 2.6 2.7 2.6 3.1 U 2.9 2.7 2.9 2.7 # 5' --> 3' X G T T G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 2.9 C 2.7 2.7 2.5 2.7 G 2.6 2.7 2.6 3.1 U 2.9 2.7 2.9 2.7 # 5' --> 3' X T A G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.0 2.5 C 2.4 2.4 2.3 2.4 G 2.0 2.0 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T C G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.5 1.8 1.5 2.0 C 2.1 2.1 2.0 2.1 G 1.6 1.6 1.6 2.1 U 2.6 2.4 2.6 2.4 # 5' --> 3' X T G G C YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.6 2.1 C 2.2 2.2 2.1 2.2 G 1.7 1.7 1.7 2.2 U 2.7 2.5 2.7 2.5 # 5' --> 3' X T T G A YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 1.9 2.4 C 2.4 2.4 2.3 2.4 G 2.0 2.0 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T G G T YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.6 C 2.7 2.7 2.6 2.7 G 2.1 2.1 2.1 2.6 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T T G G YA # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.6 C 2.7 2.7 2.6 2.7 G 2.1 2.1 2.1 2.6 U 2.9 2.7 2.9 2.7 # 5' --> 3' X T A G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.6 C 2.6 2.6 2.5 2.6 G 2.1 2.1 2.1 2.6 U 2.7 2.5 2.7 2.5 # 5' --> 3' X T C G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.1 1.8 2.3 C 2.3 2.3 2.2 2.3 G 1.3 1.3 1.3 1.8 U 2.4 2.2 2.4 2.2 # 5' --> 3' X T G G C YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.2 1.9 2.4 C 2.4 2.4 2.3 2.4 G 1.8 1.8 1.8 2.3 U 2.4 2.2 2.4 2.2 # 5' --> 3' X T T G A YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.6 C 2.6 2.6 2.5 2.6 G 2.2 2.2 2.2 2.7 U 2.7 2.5 2.7 2.5 # 5' --> 3' X T G G T YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.7 2.4 2.9 C 2.7 2.7 2.6 2.7 G 2.3 2.3 2.3 2.8 U 2.9 2.7 2.9 2.7 # 5' --> 3' X T T G G YC # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.7 2.4 2.9 C 2.7 2.7 2.6 2.7 G 2.2 2.2 2.2 2.7 U 2.9 2.7 2.9 2.7 # 5' --> 3' X T A G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.0 2.5 C 2.9 2.9 2.8 2.9 G 2.0 2.0 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T C G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 1.9 1.6 2.1 C 2.1 2.1 2.0 2.1 G 1.6 1.6 1.6 2.1 U 2.8 2.6 2.8 2.6 # 5' --> 3' X T G G C YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.7 2.0 1.7 2.2 C 1.8 1.8 1.7 1.8 G 1.7 1.7 1.7 2.2 U 2.6 2.4 2.6 2.4 # 5' --> 3' X T T G A YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.3 2.0 2.5 C 2.7 2.7 2.6 2.7 G 2.0 2.0 2.0 2.5 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T G G T YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.6 C 2.4 2.4 2.3 2.4 G 2.1 2.1 2.1 2.6 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T T G G YG # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.4 2.1 2.6 C 2.5 2.5 2.4 2.5 G 2.1 2.1 2.1 2.6 U 3.1 2.9 3.1 2.9 # 5' --> 3' X T A G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 3.1 C 2.5 2.5 2.4 2.5 G 2.5 2.5 2.5 3.0 U 2.5 2.3 2.5 2.3 # 5' --> 3' X T C G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.2 2.5 2.2 2.7 C 2.2 2.2 2.1 2.2 G 2.2 2.2 2.2 2.7 U 2.2 2.0 2.2 2.0 # 5' --> 3' X T G G C YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.4 2.7 2.4 2.9 C 2.2 2.2 2.1 2.2 G 2.2 2.2 2.2 2.7 U 2.2 2.0 2.2 2.0 # 5' --> 3' X T T G A YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 3.1 C 2.5 2.5 2.4 2.5 G 2.6 2.6 2.6 3.1 U 2.5 2.3 2.5 2.3 # 5' --> 3' X T G G T YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 3.1 C 2.7 2.7 2.6 2.7 G 2.6 2.6 2.6 3.1 U 2.9 2.7 2.9 2.7 # 5' --> 3' X T T G G YT # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.6 2.9 2.6 3.1 C 2.7 2.7 2.6 2.7 G 2.6 2.6 2.6 3.1 U 2.9 2.7 2.9 2.7