#Data table for symetric interior loops of size 2 #Free energies at 37 degrees for DNA #Data Arrangement: #For the 4x4 tables, each starting pair needs its own table. #This is the AA table: # 5' --> 3' # X # A A # T T # Y # 3' <-- 5' # Y-> # ---------------------------- # (X) A C G U # | ---------------------------- # V # (A) 1.3 2.2 0.9 1.0 # (C) 1.7 2.4 1.0 1.4 # (G) 0.4 1.0 0.3 2.0 # (U) 1.0 1.7 2.0 1.4 #An energy of "." is "infinity," i.e. not allowed. # 5' --> 3' X A A T T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 2.2 0.9 1.0 C 1.7 2.4 1.0 1.4 G 0.4 1.0 0.3 2.0 U 1.0 1.7 2.0 1.4 # 5' --> 3' X A C T G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.8 1.4 -0.4 1.0 C 1.6 2.1 1.0 1.6 G -0.2 1.0 -1.2 2.0 U 1.0 1.4 2.0 1.1 # 5' --> 3' X A G T C Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.0 1.7 0.3 1.0 C 1.5 2.0 1.0 1.0 G 0.1 1.0 -0.3 2.0 U 1.0 1.4 2.0 0.6 # 5' --> 3' X A T T A Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.2 1.7 0.2 1.0 C 1.7 2.7 1.0 1.4 G 0.2 1.0 -0.3 2.0 U 1.0 1.4 2.0 1.4 # 5' --> 3' X A G T T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.7 1.3 1.0 C 2.5 3.0 1.0 2.0 G 1.1 1.0 0.7 2.0 U 1.0 2.4 2.0 1.6 # 5' --> 3' X A T T G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.4 0.6 1.0 C 2.6 3.1 1.0 2.6 G 0.8 1.0 -0.2 2.0 U 1.0 2.4 2.0 2.1 # 5' --> 3' X C A G T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.1 2.1 0.8 1.0 C 1.7 1.8 1.0 1.4 G 0.5 1.0 0.3 2.0 U 1.0 1.4 2.0 0.6 # 5' --> 3' X C C G G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.6 1.2 -0.5 1.0 C 1.6 1.5 1.0 1.6 G -0.1 1.0 -1.3 2.0 U 1.0 1.0 2.0 0.3 # 5' --> 3' X C G G C Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.9 1.5 0.1 1.0 C 1.5 1.4 1.0 1.0 G 0.1 1.0 -0.3 2.0 U 1.0 1.0 2.0 -0.2 # 5' --> 3' X C T G A Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.0 1.5 0.1 1.0 C 1.7 2.0 1.0 1.4 G 0.3 1.0 -0.3 2.0 U 1.0 1.0 2.0 0.6 # 5' --> 3' X C G G T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.5 1.1 1.0 C 2.5 2.4 1.0 2.0 G 1.1 1.0 0.7 2.0 U 1.0 2.0 2.0 0.8 # 5' --> 3' X C T G G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 2.2 0.5 1.0 C 2.6 2.5 1.0 2.6 G 0.9 1.0 -0.3 2.0 U 1.0 2.0 2.0 1.3 # 5' --> 3' X G A C T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.9 2.1 0.5 1.0 C 1.4 1.8 1.0 1.4 G -0.1 1.0 -0.7 2.0 U 1.0 2.0 2.0 1.1 # 5' --> 3' X G C C G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.3 1.3 -0.8 1.0 C 1.3 1.6 1.0 1.6 G -0.8 1.0 -2.2 2.0 U 1.0 1.6 2.0 0.9 # 5' --> 3' X G G C C Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.6 1.6 -0.1 1.0 C 1.2 1.5 1.0 1.0 G -0.5 1.0 -1.3 2.0 U 1.0 1.6 2.0 0.3 # 5' --> 3' X G T C A Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.8 1.6 -0.2 1.0 C 1.4 2.1 1.0 1.4 G -0.4 1.0 -1.2 2.0 U 1.0 1.6 2.0 1.1 # 5' --> 3' X G G C T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 2.6 0.9 1.0 C 2.2 2.5 1.0 2.0 G 0.5 1.0 -0.3 2.0 U 1.0 2.6 2.0 1.3 # 5' --> 3' X G T C G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 2.3 0.2 1.0 C 2.3 2.6 1.0 2.6 G 0.2 1.0 -1.2 2.0 U 1.0 2.6 2.0 1.9 # 5' --> 3' X T A A T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.4 2.3 1.2 1.0 C 2.3 2.1 1.0 1.7 G 1.2 1.0 0.9 2.0 U 1.0 1.7 2.0 1.4 # 5' --> 3' X T C A G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 0.9 1.4 -0.1 1.0 C 2.1 1.8 1.0 2.0 G 0.5 1.0 -0.7 2.0 U 1.0 1.4 2.0 1.1 # 5' --> 3' X T G A C Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.1 1.7 0.5 1.0 C 2.1 1.8 1.0 1.4 G 0.8 1.0 0.3 2.0 U 1.0 1.4 2.0 0.6 # 5' --> 3' X T T A A Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 1.7 0.4 1.0 C 2.2 2.4 1.0 1.7 G 0.9 1.0 0.3 2.0 U 1.0 1.4 2.0 1.4 # 5' --> 3' X T G A T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 2.7 1.5 1.0 C 3.1 2.8 1.0 2.4 G 1.8 1.0 1.3 2.0 U 1.0 2.4 2.0 1.6 # 5' --> 3' X T T A G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.4 0.9 1.0 C 3.1 2.8 1.0 3.0 G 1.5 1.0 0.3 2.0 U 1.0 2.4 2.0 2.1 # 5' --> 3' X G A T T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 3.1 1.5 1.0 C 2.4 2.8 1.0 2.4 G 0.9 1.0 0.3 2.0 U 1.0 3.0 2.0 2.1 # 5' --> 3' X G C T G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.3 2.3 0.2 1.0 C 2.3 2.6 1.0 2.6 G 0.2 1.0 -1.2 2.0 U 1.0 2.6 2.0 1.9 # 5' --> 3' X G G T C Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 2.6 0.9 1.0 C 2.2 2.5 1.0 2.0 G 0.5 1.0 -0.3 2.0 U 1.0 2.6 2.0 1.3 # 5' --> 3' X G T T A Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.8 2.6 0.8 1.0 C 2.4 3.1 1.0 2.4 G 0.6 1.0 -0.2 2.0 U 1.0 2.6 2.0 2.1 # 5' --> 3' X G G T T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 G 3.0 3.0 3.0 3.0 U 3.0 3.0 3.0 3.0 # 5' --> 3' X G T T G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 G 3.0 3.0 3.0 3.0 U 3.0 3.0 3.0 3.0 # 5' --> 3' X T A G T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.1 3.1 1.8 1.0 C 2.7 2.8 1.0 2.4 G 1.5 1.0 1.3 2.0 U 1.0 2.4 2.0 1.6 # 5' --> 3' X T C G G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.6 2.2 0.5 1.0 C 2.6 2.5 1.0 2.6 G 0.9 1.0 -0.3 2.0 U 1.0 2.0 2.0 1.3 # 5' --> 3' X T G G C Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 1.9 2.5 1.1 1.0 C 2.5 2.4 1.0 2.0 G 1.1 1.0 0.7 2.0 U 1.0 2.0 2.0 0.8 # 5' --> 3' X T T G A Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 2.0 2.5 1.1 1.0 C 2.7 3.0 1.0 2.4 G 1.3 1.0 0.7 2.0 U 1.0 2.0 2.0 1.6 # 5' --> 3' X T G G T Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 G 3.0 3.0 3.0 3.0 U 3.0 3.0 3.0 3.0 # 5' --> 3' X T T G G Y # 3' <-- 5' # Y # ---------------------------- A C G U # ---------------------------- A 3.0 3.0 3.0 3.0 C 3.0 3.0 3.0 3.0 G 3.0 3.0 3.0 3.0 U 3.0 3.0 3.0 3.0