# 5' --> 3' # AX # A # 3' <-- 5' # X-> # ---------------------------- # A C G U # ---------------------------- # . . . . # 5' --> 3' AX A # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' AX C # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' AX G # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' AX T # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- +4.3 +6.3 +2.5 +2.6 # 5' --> 3' CX A # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' CX C # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' CX G # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -8.0 -2.5 -3.1 -3.9 # 5' --> 3' CX T # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' GX A # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' GX C # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -1.9 -0.2 -4.0 -5.5 # 5' --> 3' GX G # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' GX T # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -1.9 -0.2 -4.0 -5.5 # 5' --> 3' TX A # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -5.3 +2.0 -4.8 +0.9 # 5' --> 3' TX C # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' TX G # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -8.0 -2.5 -3.1 -3.9 # 5' --> 3' TX T # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' A AX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' A CX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' A GX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' A TX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- +0.8 +2.0 +1.5 +1.1 # 5' --> 3' C AX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' C CX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' C GX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -4.6 -4.2 -4.7 -5.0 # 5' --> 3' C TX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' G AX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' G CX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -6.2 -3.3 -5.1 -0.9 # 5' --> 3' G GX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' G TX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -6.2 -3.3 -5.1 -0.9 # 5' --> 3' T AX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -0.9 -0.6 -2.5 -9.0 # 5' --> 3' T CX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . . # 5' --> 3' T GX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- -4.6 -4.2 -4.7 -5.0 # 5' --> 3' T TX # 3' <-- 5' # X # ---------------------------- A C G U # ---------------------------- . . . .