Welcome to the DuplexFold Web Server
The DuplexFold server is similar to the Bimolecular Fold server; it folds two sequences, either RNA or DNA, into their lowest hybrid free energy conformation.
The Bimolecular Fold server allows formation of intramolecular pairs if desired, but the DuplexFold server does not allow formation of intramolecular pairs.
Note that if an error is encountered in duplex folding, it may still be possible to fold one or both component sequences independently without errors.
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If you need specific help using the DuplexFold server, please click here.