Welcome to the AllSub Web Server

The AllSub server takes a sequence file of nucleic acids, either DNA or RNA, and folds it into its lowest free energy conformation. In addition, a variety of structures are generated, called suboptimal structures, whose free energy values are very close to the lowest free energy value. This server can generate many structures or only a few; very similar structures or more divergent conformations, based on the values of its options. Note that this calculation may take a significant amount of time, depending both on the size of the sequence and the number of suboptimal structures generated.

If you plan to leave this page while waiting for calculations to complete, please make sure you have entered a valid email address below. Leaving this page without entering a valid email address will render results inaccessible.

If you need specific help using the AllSub server, please click here.

Note: The maximum sequence length has been increased for several tools. Please see Sequence Limits for details.

Select Sequence Input:

- OR -
Enter your sequence title and content below (replaces upload if present).
Please enter nucleotides only, no headers or comments in content.
Valid nucleotides are A, C, G, T, U, and X (unknown nucleotide). Lower case nucleotides are forced single stranded in calculation.



Select Nucleic Acid Type:



Select AllSub Options:

If a default value is left blank, the value is treated as if it was not changed at all.



Designate Address to Email Results: