## Terminal Mismatch ΔG° |
||||

5'––>3' |
||||

(X) Y–> | A | C | G | U |

(A) | –0.8 | –1.0 | –0.8 | –0.4 |

(C) | –0.6 | –0.7 | –1.7 | –0.7 |

(G) | –0.8 | –1.6 | –0.8 | –0.1 |

(U) | –0.6 | –0.8 | –0.9 | –0.8 |

5'––>3' CX GY 3'<––5' |
||||

(X) Y–> | A | C | G | U |

(A) | –1.5 | –1.5 | –1.4 | –1.6 |

(C) | –1.0 | –1.1 | –2.8 | –0.8 |

(G) | –1.4 | –1.9 | –1.6 | –0.9 |

(U) | –1.6 | –1.4 | –1.6 | –1.2 |

5'––>3' GX CY 3'<––5' |
||||

(X) Y–> | A | C | G | U |

(A) | –1.1 | –1.5 | –1.3 | –1.9 |

(C) | –1.1 | –0.7 | –2.9 | –0.5 |

(G) | –1.6 | –2.8 | –1.4 | –1.0 |

(U) | –1.7 | –1.0 | –2.0 | –0.7 |

5'––>3' GX UY 3'<––5' |
||||

(X) Y–> | A | C | G | U |

(A) | –0.3 | –1.0 | –0.8 | –0.8 |

(C) | –0.6 | –0.7 | –2.0 | –0.7 |

(G) | –0.6 | –1.6 | –0.8 | 0.0 |

(U) | –0.9 | –0.8 | +1.8 | –0.8 |

5'––>3' UX AY 3'<––5' |
||||

(X) Y–> | A | C | G | U |

(A) | –1.0 | –0.8 | –1.1 | –0.8 |

(C) | –0.7 | –0.6 | –1.9 | –0.5 |

(G) | –1.1 | –1.6 | –1.2 | –0.5 |

(U) | –0.4 | –0.6 | –0.8 | –0.5 |

5'––>3' UX GY 3'<––5' |
||||

(X) Y–> | A | C | G | U |

(A) | –1.0 | –0.8 | –1.1 | –0.5 |

(C) | –0.7 | –0.6 | –1.0 | –0.5 |

(G) | –0.5 | –0.9 | –0.8 | –0.8 |

(U) | –0.1 | –0.6 | 0.0 | –0.5 |