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Turner 1999

Bulge Loops

Example 1

 

 

example structure        

∆G°37 = ∆G°37(Watson-Crick Pairs) + ∆G°37 intermolecular initiation + ∆G°37(Bulge Loop)


∆G
°37 = ∆G°37(GC followed by CG) + ∆G°37(CG followed by CG) + ∆G°37 intermolecular initiation + ∆G°37 bulge initiation(1) + ∆G°37(CG followed by GC)

 

∆G°37 = –3.42 kcal/mol 3.26 kcal/mol + 4.09 kcal/mol + 3.8 kcal/mol – 2.36 kcal/mol

 

∆G°37 = –1.2 kcal/mol